35 Gatehouse Drive, A2

Waltham, MA 02451


July 6, 2020


United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, DC 20549


Attention:   Office of Life Sciences
Re:   Morphic Holding, Inc.
    Registration Statement on Form S-3
    Filed July 1, 2020
    File No. 333-239607


  Requested Date: July 8, 2020
  Requested Time: 4:00 p.m. Eastern Time


Ladies and Gentlemen:


Morphic Holding, Inc. (the “Registrant”) hereby requests that the Securities and Exchange Commission (the “Commission”) take appropriate action to make the above-captioned Registration Statement on Form S-3 effective at the “Requested Date” and “Requested Time” set forth above or as soon thereafter as practicable.


The Registrant hereby authorizes Rob Freedman or Julia Forbess, both of whom are attorneys with the Registrant’s outside legal counsel, Fenwick & West LLP, to orally modify or withdraw this request for acceleration.


  Morphic Holding, Inc.
  By: /s/ Marc Schegerin
    Marc Schegerin
    Chief Financial Officer


cc: Praveen P. Tipirneni, Chief Executive Officer  
  Morphic Holding, Inc.  
  Rob Freedman, Esq.  
  Julia Forbess, Esq.  
  Fenwick & West LLP